Basic Dimension
Disclaimer:
- Genetics and genealogy are serious professions with a lot of hidden rules which can change the calculations considerably.
- Genetics and genealogy are serious professions with a lot of hidden rules which can change the calculations considerably.
Chromosomes:
http://abri.une.edu.au/online/pages/inbreeding_coefficient_help.htm
http://abri.une.edu.au/online/pages/inbreeding_coefficient_help.htm
Explanation of inbreeding in animal populations relies on a few basic genetic principles. Genetic information is stored in Chromosomes. Chromosomes are made up of DNA. Genes are sections of DNA and occur in pairs. A particular gene will occur at a particular site (locus, plural is loci) in the DNA of a particular Chromosome. The different forms of a gene (usually 2) that can occur at that locus are called alleles. Where both alleles are the same at the locus, they are called homozygous. Where the alleles are different, they are called heterozygous. In general, the two alleles will have an equal influence on the performance of an animal. That is, the heterozygous form (both alleles are present) tends to have performance midway between the two homozygous forms. In a few cases, one allele will have the main (dominant) effect on an animal, while the other allele will only have an effect in its homozygous form. These are called dominant and recessive genes.
Coefficient of Inbreeding:
The Coefficient of Inbreeding (as proposed by Sewell Wright in 1922) is the probability that two alleles at a randomly chosen locus are identical by descent. Note that alleles may be identical for other reasons, but the inbreeding coefficient is just looking at the mathematical probability that the alleles have come from a common ancestor.
The Coefficient of Relationship (R) looks more a descriptive statistic of consanguinity relations within families. For example a father and his child have 50% of their genes in common. The same for two siblings. So it is not directly a probability for specific individual situations.
The Inbreeding Coefficient:
The Coefficient of Relationship:
The Coefficient of Relationship (R) looks more a descriptive statistic of consanguinity relations within families. For example a father and his child have 50% of their genes in common. The same for two siblings. So it is not directly a probability for specific individual situations.
Coeff. of Inbreeding versus Coeff. of Relatedness:
The Coefficient of Inbreeding (as proposed by Sewell Wright in 1922) is the probability that two alleles at a randomly chosen locus are identical by descent. Note that alleles may be identical for other reasons, but the inbreeding coefficient is just looking at the mathematical probability that the alleles have come from a common ancestor.
The Coefficient of Relationship (R) looks more a descriptive statistic of consanguinity relations within families. For example a father and his child have 50% of their genes in common. The same for two siblings. So it is not directly a probability for specific individual situations.
Brother-Sister Relationships:
Realize that brother-sister relationships have been common in the evolution. But those were random phenomena in general. What is devastating in inbreeding populations is the stacking of effects over many generations, so that the family genome is systematically impoverished and the group's chances of survival are undermined.
Autosomal disorders
Islam looks like an autosomal recessive disorder:
http://www.mayoclinic.org/autosomal-recessive-inheritance-pattern/img-20007457
To have an autosomal recessive disorder, you inherit two mutated genes, one from each parent. These disorders are usually passed on by two carriers. Their health is rarely affected, but they have one mutated gene (recessive gene) and one normal gene (dominant gene) for the condition. Two carriers have a 25 percent chance of having an unaffected child with two normal genes (left), a 50 percent chance of having an unaffected child who also is a carrier (middle), and a 25 percent chance of having an affected child with two recessive genes (right).
To have an autosomal recessive disorder, you inherit two mutated genes, one from each parent. These disorders are usually passed on by two carriers. Their health is rarely affected, but they have one mutated gene (recessive gene) and one normal gene (dominant gene) for the condition. Two carriers have a 25 percent chance of having an unaffected child with two normal genes (left), a 50 percent chance of having an unaffected child who also is a carrier (middle), and a 25 percent chance of having an affected child with two recessive genes (right).
Inbreeding is a malicious form of natural selection, which apparently has left deep scars on the Muslim population. The whole package of long lasting inbreeding terror likely has caused a large and similar to autosomal recessive disorder syndrome. This means at numerous places in the Muslim genome, there must have formed a pre-selection of homozygous alleles (rr), which are characteristic for inbreeding. In other words, RR has been removed and rr remains.
Religion is monotheistic male terror against females:
'Religion' as a means of controlling female sexuality develops into all directions because of magical derivatives: HR = f(SR). These have nothing rationally to do with breeding anymore, like Reincarnation in the example below (in which Eve was perfectly right):
Human Religion (Islam) started as a function of Sexual Religion (Inbreeding). The instinctive incentive was to stop autosomal recessive disorders by outcrossing. Just as happened for 14 million years since the first bipedal primates:
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